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Could you ask her to call me? how long does it take for fluconazole to work on oral thrush Coral reefs are disappearing at an unprecedented rate, so it is hoped that the newly-launched global database – freely available on line to both the scientific community and the general public – will lead to a greater understanding of the changes to reefs as a result of over-exploitation, pollution and climate change. It is estimated that 500 million people globally depend on coral reefs for food and income but between one third and one half of corals around the world have been lost in the last 50 years.